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DINNER LECTURE- BENEFITS OF PSILOCYBIN IN MOOD, MIND AND MEDICINE

The Fox Restaurant & Brewery
310 South Carson Street
Carson City, NV 89701

Wednesday, June 18, 2025 at 6:00pm PT - 8:00pm PT
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310 South Carson Street, Carson City, NV 89701

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Topic

Discussion of the benefits of psilocybin in mood, mind, and medicine

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Psilocybin is a 5-HT2A receptor agonist, also modulating dopamine and glutamate pathways.

5-HT2A receptors are predominantly expressed in the brain, but also found in the central and peripheral nervous systems. These receptors regulate emotional, cognitive, and neuropsychiatric processes. Psilocybin disrupts associative brain networks and their sensory integration, while enhancing cortical activity and promoting a high-entropy brain state.

Additional mechanisms include hypothalamic-pituitary-adrenal axis modulation, endocrine regulation, and anti-neuroinflammatory effects-particularly through microglial and astrocyte activity. One of psilocybin's most promising effects is the enhancement of neuropsychological plasticity. While synaptic plasticity varies throughout the human lifespan, dysregulated plasticity is implicated in numerous neuropsychiatric disorders.

Speakers

Leah Linder
Leah Linder ND

With a background in biochemistry and emergency medicine, Leah is a naturopathic physician trained in psychedelic assisted therapy with deep expertise in natural supplement formulation and manufacture. She is a Master Gardener, experienced educator, and ordained minister.

Pam Conboy

With a background in biology, Pam was trained as a clinical laboratorian and is currently a doctoral student in naturopathic medicine. She is an IIN certified health coach, trained psychedelic facilitator, medical marketing|business development entrepreneur, and ordained minister.

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